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Every household (should) have olive oil in it, and while it is safe for vaginal use and anal sex, there are a few risks you should be aware of. For one, oil-based lubes—both the manmade and Exposure to a lubricant with a higher osmolality than normal vaginal secretions can result in vaginal tissue which literally shrivels up because the moisture in those cells is pulled out. This process leads to irritation and a breakdown of the mucous membrane barrier which protects the vagina from infection.